多层螺旋CT肺密度测定与肺气肿患者肺功能的相关性研究

摘要

Objective To investigate the correlation between lung density measured by MSCT and pulmonary function tests in patients with pulmonary emphysema. Methods The lung density and pulmonary function of 45 patients with pulmonary emphysema and 40 cases in control group were detected. The results of lung density measured by MSCT and pulmonary function tests were compared in the research. Results The VD of total lung measured by MSCT with pulmonary emphysema in expiratory and inspiratory time were significantly correlated to TLC, FEV1 and FEV1/FVC ( P ＜ 0. 01 ), but significantly negatively correlated to RV/TLC ( P ＜ 0. 01 ). The MLD of the total lung in the inspiratory time showed no correlation with PFT indices ( P ＞ 0. 05 ). Conclusion The lung density measured by MSCT was closely related to pulmonary function tests in pulmonary emphysema disease.%目的 探讨多层螺旋CT肺密度测定与肺气肿患者肺功能的相互关系.方法 对45例肺气肿患者及40例对照组人员的CT肺密度和肺功能进行测定,并将CT肺密度测定结果与肺功能结果进行对照研究.结果 肺气肿患者CT呼、吸气相 VD与TLC、FEV1及FEV1/FVC呈显著正相关(P<0.01),而与RV/TLC呈显著负相关(P<0.01).吸气相全肺MLD与PFT指标无相关性(P>0.05).结论 对于肺气肿疾病多层螺旋CT肺密度测定与肺功能检测有着密切的关系.