新生儿坏死性小肠结肠炎预后相关因素分析

摘要

Objetive To explore the prognostic factors related to the prognosis of neonatal necrotizing enterocolitis(NEC). Methods A retrospective study was given to the 1 24 cases with NEC diagnosed and trea-ted in our hospital from Dec 2008 to Dec 201 2.According to the prognosis,all the cases were divided into 2 groups:survival group and death group.Compared the two groups of clinical data,the main factors infiuencing the NEC patients’prognosis were studied. Results The risk factors included birth weight,absence of bowel sounds,the WBC ≥20 ×1 09/L or the WBC<4 ×1 09/L,metabolic acidosis,diffuse peritonitis,neonatal re-spiratory distress syndrome (NRDS),and other factors.The differences between the two groups had statistical significance(P<0.05).Conclusion Very low birth weight,absence of bowel sounds,the WBC≥20 ×109/L or the WBC <4 ×1 09/L,metabolic acidosis,diffuse peritonitis,NRDS,etc are the main factors influencing the NEC patients prognosis,and should be found as early as possible so that comprehensive treatment could be provided and survival rate of infants with NEC child could be increased.%目的：探讨影响新生儿坏死性小肠结肠炎（NEC）患儿预后的相关因素。方法对本院2008年12月至2012年12月收治的124例NEC患儿进行回顾性分析。根据患儿的预后分为死亡组与存活组，比较两组临床资料，分析影响其预后的主要因素。结果两组在出生体重、肠鸣音减弱或消失、WBC≥20×109/L或＜4×109/L、代谢性酸中毒、弥漫性腹膜炎、新生儿呼吸窘迫综合征（NRDS）等因素上比较，差异均有统计学意义（P＜0.05）。结论极低出生体重、肠鸣音减弱或消失、WBC≥20×109/L或＜4×109/L、代谢性酸中毒、弥漫性腹膜炎、NRDS等是影响NEC患儿预后的主要因素，应及早发现并采取综合治疗，以提高NEC患儿存活率。