Objective To investigate the imaging features of fudus flurorescein angiography (FFA) combined with optical coherence tomopraphy (OCT) in the initial stage of Vogt-Koyanagi-Harada syndrome (VKH) . Methods 27 cases (54 eyes) VKH patients' clinical data were observed, FFA and OCT imaging features were compared and analyzed. Results FFA image display speckle-like low fluorescence in early artery stage, large number of needlepoint tiny strong fluorescence were showed at vein period in posterior pole of retina and around the optic disc, with imaging time delay, the fluorescence leakage and gradually expand, fusion, in the late stage the characteristic of multi-lake retinal fluorescence accumulated stove were shown. OCT images showed multiple retinal neural epithelium detachment and nerve epithelial thickening. Conclusions FFA and OCT both has its advantages in diagnosis of VKH, applications can provide research material for the pathogenesis of VKH syndrome, which greatly improved the diagnostic value of imaging examination.%目的 探讨荧光素眼底血管造影 (FFA) 联合相干光断层扫描 (OCT) 在初发期Vogt-小柳原田综合征 (VKH) 检查中的影像特征.方法 对27例 (54只眼) VKH患者的临床资料进行观察, 对比分析其FFA及OCT检查影像特征.结果 FFA图像显示动脉前期视网膜斑点状低荧光, 静脉期后极部及视盘周围大量针尖样细小点状强荧光, 随造影时间延迟, 荧光渗漏明显并逐渐扩大、融合, 晚期出现特征性的多湖状视网膜下荧光积存灶.OCT图像显示多发性视网膜神经上皮层脱离、神经上皮增厚.结论 FFA与OCT在VKH诊断中各具优势, 两者联合应用可为VKH的发病机制提供研究资料, 极大地提高了影像学检查的诊断价值.
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