湿润烧伤膏在伤口肉芽组织水肿创面换药中的应用研究

摘要

目的：探讨湿润烧伤膏在伤口肉芽组织水肿创面换药中的应用，为烧伤患者的治疗提供更好的依据。方法选取我院2011年12月～2013年12月收治的96例中小面积烧伤创面患者进行研究，按照临床试验随机对照的原则将患者分为对照组和观察组，每组48例。对照组采用10％的氯化钠液进行换药创面的清洗，每2 d换药1次。观察组采用湿润烧伤膏进行换药治疗，每3d换药1次。观察两组疗效、创面愈合时间、换药次数及并发症发生率，并进行比较。结果观察组治疗后痊愈28例，有效17例，无效3例，总有效率为93．75％。对照组痊愈19例，有效15例，无效14例，总有效率为70．83％，两组比较有显著性差异（P＜0．05）；观察组创面愈合平均时间、换药次数和住院时间分别为11．4±4．6d、8．3±3．7次、13．7±3．3d，显著短于对照组的23．4±4．8d、13．6±3．4次和26．7±3．3d，两组比较有显著性差异（P＜0．05）；观察组治疗期间无创面感染，治疗后1例创面瘢痕化，占2．08％。对照组治疗期间3例创面感染，占6．25％，4例创面瘢痕化，占8．33％，两组比较有显著性差异（P＜0．05）。结论选用湿润烧伤膏用于肉芽组织水肿创面换药，既可明显缩短伤口愈合时间，减少伤口换药次数；又可提高患者治疗后的疗效，可应用于临床。%Objective To study the effect of application of moisture exposed burn ointment (MEBO) wound granulation tissue edema in the wound dressing .It could provide a better way to treat the wound .Methods 96 patients with the wound from December 2011 to December 2013 in our hospital were to be studied .They were divided into two groups by randomly . The control group received 10% of the sodium chloride dressing the wound cleaning ,dressing 1 every 2 d ,the observation group conducted dressing MEBO treatment ,dressing 1 every 3 d efficacy were observed in the wound healing time ,dressing times and complication rates .Results Observed after treatment cured 28 cases ,effective in 17 cases ,3 cases ,the total ef-fective rate was 93 .75% ,while the control group cured 19 cases ,effective in 15 cases ,14 cases ,total effective rate was 70 .83% ,compared to the two groups ,the difference was significant ,P< 0 .05 ;observation group average healing time , number of switches and hospitalization time was 11 .4 ± 4 .6 d ,8 .3 ± 3 .7 times ,13 .7 ± 3 .3 d ,significantly shorter than the control group 23 .4 ± 4 .8 d ,13 .6 ± 3 .4 times and 26 .7 ± 3 .3 d ,compared the two groups ,the difference was significant(P<0 .05);no wound infection during the observation group therapy patients ,after treatment there is one case of scar ,the rate was 2 .08% ,while the control group during the treatment of wound infection in 3 patients (6 .25% ) ,4 cases scarring ,ac-counting for 8 .33% ,compared to the two groups ,the difference was significant(P<0 .05) .Conclusions Selection of ME-BO wound dressing for granulation tissue edema ,can significantly shorten healing time ,reduce the number of wound dress-ing ;but also improve the efficacy of the patient after treatment ,worthy of recommendation .