颅内孤立性纤维瘤2例报告并文献复习

摘要

Objective To explore the image,pathology,clinical features and surgical effect of intracranial solitary fibrous tumors(SFT),in order to improve the diagnosis and differential diagnosis.Method The clinical data of 2 patients with SFT proved by pathology were analyzed retrospectively.Results 2 patients received total resection of SFT and were followed up 3 years,and had good prognosis.There were 2 SFTs scanned by MRI.All of the 2 cases were isointense on T1 WI,and were mixed intensity on the T2 WI.2 cases showed heterogeneously intense enhancement.Immunohistochemical staining showed that CD34-positive,CD99-positive,vimentin-positive.Conclusion Intracranial SFT has some characteristics on MRI,yet final diagnosis should be based on histopathology and immunohistochemislry examinalions.%目的：探讨颅内孤立性纤维瘤（SFT）的影像学、病理学、临床特征和手术疗效，旨在提高对该病的诊断和鉴别诊断。方法回顾性分析经临床病理证实的2例 SFT 患者的临床资料，并回顾相关文献。结果2例患者均手术全切除肿瘤，术后随访3年，肿瘤无复发。MRI 示肿瘤 T1 WI 多为等信号，T2 WI 多为混杂信号，增强扫描后不均匀强化。病理免疫组化染色检查：CD34（＋），CD99（＋），Vim（＋）。结论颅内 SFT 的MRI 表现有一定特征性，确诊需依靠病理学及免疫组织化学检查，治疗以手术全切除为主。