黄芪注射液穴位注射防治卵巢癌化疗后骨髓抑制的临床疗效观察

摘要

目的：观察黄芪注射液足三里穴位注射对卵巢癌化疗患者骨髓抑制的防治作用。方法：采用随机对照试验临床研究方法，将114例卵巢癌化疗患者随机分为治疗组56例，对照组58例，两组患者均采用常规化疗方案，治疗组在常规化疗基础上加用足三里注射黄芪注射液，两组同期观察一化疗周期，比较两组患者化疗后骨髓抑制情况和Karnorsky评分，并评价其安全性。结果：一疗程结束后两组比较，治疗组在白细胞、中性粒细胞及血红蛋白数目方面优于对照组，差异具有统计学意义（P＜0．05），但两组Karnorsky评分及肝肾功能差异无统计学意义（ P＞0．05）。结论：黄芪注射液足三里穴位注射对卵巢癌化疗患者骨髓抑制具有保护作用。%Objective:To investigate the effect of Zusanli(ST36) point injection of astragalus on preventing and curing the bone marrow suppression after chemotherapy of ovarian cancer.Methods:This research was random-ized and controlled approach.There were 114 patients with chemotherapy of ovarian cancer.56 cases and 58 ca-ses were randomly allocated into a treatment group and a control group,respectively.Both groups received chem-otherapy,and the treatment group also received Zusanli point injection of astragalus.Observe a cycle of chemo-therapy and compare patients in two groups with bone marrot suppression after chemotherapy , the point of Karnorsky and safety.Results:A comparison between two groups after one course of treatment showed that the number of white blood cells,neutrophils and hemoglobin in the treatment group were superior to those in the control group,and the difference was statistically significant(P<0.05).However,the points of Karnorsky and hepatorenal and kidney function were not statistically significant(P>0.05).Conclusion:Zusanli point injection of astragalus for patients with chemotherapy of ovarian cancer can effectively prevent the bone marrow suppres-sion.