Regulatory effects of dietary L-Arg supplementation on the innate immunity and antioxidant ability in broiler chickens

摘要

cqvip:Here, we investigated the effect of dietary arginine(Arg) supplementation on innate immunity and the antioxidant ability of broiler chickens. The experiment was designed as a single-factorial arrangement(n=8 cages/treatment, six birds/cage), and we used four dietary Arg concentrations(10.0, 15.0, 20.0 or 25.0 g kg–1). On day 21, the birds were killed to obtain spleen, cecal tonsil and liver samples to determine the gene expression and antioxidant characteristics. Increasing the Arg concentration linearly decreased(P0.05). No significant(P>0.05) effect was found on the activity of superoxide dismutase(SOD) in the liver. Thus high levels of Arg supplementation(>20.0 g kg^(–1)) may potentially suppress the innate immunity of broiler chickens, and dietary Arg supplementation enhances the antioxidant activity in broiler chickens.