Objective: To evaluate the therapeutic effect of combining use of acupuncture and drugs on rheumatoid arthritis(RA) in the early and the active stages of by the imaging of bone and joint with 99m TC-methlene diphosphate(MDP). Methods: 102 cases of RA in the early and the active stages were randomly allocated into the compound Fengshining group (Group A),acupuncture group(Group B), and compound Fengshining plus acupuncture group(Group C).They were treated for 30 days. All patients were examined before treatment and after treatment by 99m TC-MDP imaging of the whole body, hands and feet, and analyzing method of random interested region was used to count the ratio of radioactivity in the affected area of RA to radioactivity in adjacent normal bone(T/TN). Meanwhile, joint swelling index, joint tenderness index, morning stiffness, gripping force, and erythrocyte sedimentation rate (ESR) were also observed. Results: T/TN of the Group A after treatments had no significant difference comparing with that before treatment(t = 1.35, P＞0.05), while the Group B and C had significant differences(t = 5.31, t=8.97, P＜0.01). The changes of clinical and experimental examination in the Group C had more significant differences than those in the Group A and B(P＜0.05).Conclusion: Acupuncture therapy could promote RA recovery, and combining use of acupuncture and compound Fengshining had better effect.%目的:运用99m TC-MDP骨关节显像对比评价针药配合治疗早期和活动期类风湿关节炎(RA)的疗效.方法:将102例临床确诊的早期和活动期RA患者随机平分为复方风湿宁组(A组)、针刺组(B组)和复方风湿宁加针刺组(C组),疗程30 d,治疗前后行99m TC-MDP全身及手足局部骨显像,用感兴趣区分析法计算类风湿关节区和邻近正常骨骼的放射性比(T/TN),同时观察关节肿胀指数、关节压痛指数、晨僵、握力、进行ESR检查.结果:T/TN比A组治疗前后无显著差异(t=1.35,P＞0.05),B、C组则有明显改善(t=5.31,t=8.97,P＜0.01);C组治疗前后临床和实验室检查的改变(P＜0.05),比A组、B组更有显著性(P＜0.05).结论:针刺可促进类风湿关节炎的修复,针刺加复方风湿宁治疗疗效最佳.
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