'白芥子涂法'复方及单味药抗豚鼠哮喘效应的比较

摘要

目的 比较穴位敷贴方剂"白芥子涂法"复方及各单味药抗豚鼠哮喘的效应.方法 采用卵清白蛋白复制豚鼠哮喘模型,观察"白芥子涂法"复方及其主要组成药物对卵清白蛋白诱导后豚鼠哮喘潜伏期及哮喘发作程度的影响.结果 各组定喘作用强弱依次为复方>白芥子>甘遂、延胡索、细辛.控制哮喘的效应与药物本身的止喘作用及其对皮肤的刺激程度有关.结论 "白芥子涂法"复方效果优予单方;单方药物中白芥子预防与控制实验性哮喘的作用最强.%Objective To compare the anti-asthmatic effects of acupoint sticking therapy with Baijiezi tufa from compound Chinese traditional medicine and single Chinese herb on guinea pigs.Methods Ovalbumin(OVA)-sensitized guinea pigs were treated by acupoint sticking therapy with compound Chinese traditional medicine or single herb. The incubation period and degree of asthma attack were observed after treatment. Results The efficacy of treatment was in an order of compound ＞Baijiezi＞Gansui, Yanhusuo and Xixin. The anti-asthmatic effect was related to the phamacological characteristics of the drug and its degree of skin stimulation. Conclusion The anti-asthmatic effect of compound is better than that of single herb. Among the single herbs, Baijiezi is the strongest in preventing and controlling asthma.