目的 分析新疆维吾尔自治区人民医院戊型肝炎病例流行病学特征.方法 选取2015年1月至2017年12月就诊于新疆维吾尔自治区人民医院传染科的1 931例疑似戊型肝炎患者作为研究对象.收集整理研究对象的临床资料,采集研究对象空腹静脉血,分离血清,采用酶联免疫吸附试验(ELISA)检测血清抗-HEV-IgG和抗-HEV-IgM,分析戊型肝炎的流行病学特征.结果 1 931例疑似戊型肝炎患者中抗-HEV-IgG阳性396例,阳性率为20.51％;抗-HEV-IgM阳性16例,阳性率为0.83％.汉族人群检测阳性率为18.99％(161/848),维吾尔族人群检测阳性率为21.70％(235/1 083),差异无统计学意义(x2=1.98,P=0.159).40～59岁患者占全部戊肝患者的48.99％(194/396),其次为60～69岁患者,占19.19％(76/396).结论 该院2015-2017年戊型肝炎患者总体阳性率偏高,以40～59岁中年人群为主,应针对该部分人群采取综合措施,加强防控工作.%Objective To analyze the epidemiological characteristics of hepatitis E in the People's Hospital of Xinjiang Uygur Autonomous Region in Xinjiang.Methods A total of 1 931 suspected hepatitis E infected patients who visited to the department of Infectious Diseases in People's Hospital of Xinjiang Uygur Autonomous Region from January 2015 to December 2017 were selected as the study subjects.The venous blood samples were collected to detect serum anti-HEV-IgG and anti-HEV-IgM by ELISA.The epidemiological data were also analyzed.Results Among the samples of 1 931 suspected hepatitis E infected patients,396 samples were anti-HEV-IgG positive with a positive rate of 20.51％ while samples were anti-HEV-IgM positive and the positive rate was 0.83％.The positive rate of Han and Uyghur were 18.99％ (161/848) and 21.70％ (235/1 083),respectively.The difference was not statistically significant (x2=1.98,P=0.159).The positive rate of anti-HEV-IgG was 48.99％ (194/396) in 40-59 years old group and was 19.19％ (76/396) in 60-69 years old group.Conclusions The results suggest that HEV-positive rates were much higher among patients aged from 40 to 59 years old.It should take steps of preventing the infections among these patients.
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