472例疑似宫颈病变患者HPV亚型检测结果分析

摘要

目的 分析该地区各年龄段疑似宫颈病变患者人乳头瘤病毒(HPV)感染情况及HPV亚型的分布情况.方法 运用核酸分子快速导流杂交法对472例疑似宫颈病变患者进行HPV分型.结果 472例疑似宫颈病变患者中,以30～39岁年龄段感染率最高;在HPV各亚型中,以HPV52、16、58高危型所占比例最高.结论 各地区HPV感染存在地区分布差异,该地区与其他地区亚型分布有一定差异,但与国内调研结果总体基本一致.在年龄分布上HPV的感染以中年期女性为主,与女性性活跃程度有关.%Objective To analyze the prevalence of human papilloma virus (HPV) and its subtypes in suspected patients with cervical diseases . Methods 472 cases of suspected patients with cervical diseases were detected for HPV subtype by using nucleic acid flow-through hybridization .Results In the total of 472 patients , infection rate of subjects at 30-39 years old was the highest . In all HPV subtypes , high risk HPV , including HPV52, 16 and 58 , were with the highest proportion .Conclusion The infection rate of HPV might be different for different regions , and the distribution of HPV subtypes might be with a little difference , compared with other regions , but consistent with research results in China . HPV could mainly infect middle age woman , and it might be related with sexual activity of females .