Objective To understand the basic situation of blood donors and their anti-HIV antibody screening in a hospital of Madagascar during 2008- 2009 in order to provide the reference information for giving better medical aid and promoting the devel-opment of the clinical transfusion in Madagascar.Methods The blood doner′s personal informations were understood by inquiry and the anti-HIV antibody was detected by the rapid testing,the results were recorded,the constituent ratio of the data was calcu-lated and the chi-square test was performed.Results There were 2 298 blood donors including teenages less than 15 years old dur-ing 2008-2009,female doners were more than male donors,among them 366 cases were pregrant women.The blood donors from village were more than those from city,the education level was dominated by the middle school students,accounting for 51.65%. There were 22 tuberculosis patients in 2008,none in 2009.The detection rate of anti-HIV antibody was 0.04% for these 2 years. Conclusion The protection on the blood donors in Africa area is not optimistic.The phenomenon of pregrant women and teenages as the blood donors exists in Madagascar.%目的:了解马达加斯加某医院2008~2009年献血员的基本情况和艾滋病毒抗体筛查情况,为以后更好的医疗援助马达加斯加及促进其临床输血领域的发展提供参考信息。方法口头询问方式获取献血员的基本信息,采用快速法检测 HIV 抗体,记录结果,计算数据的构成比,并进行χ2检验。结果2008~2009年共2298名献血员,有15岁及以下的献血者,女性献血员多于男性,其中有366名是孕妇;农村多于城市,文化程度以中学为主,占51.65%。2008年有22名结核病患者,2009年为0。两年艾滋病毒抗体阳性检出率为0.04%。结论非洲地区对献血者的保护不容乐观,存在孕妇和青少年献血的现象。
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机译:结合人CD20的人单克隆抗体,该抗体能够在存在补体的情况下诱导表达CD2的细胞的补体依赖性细胞毒性,并且包含根据EP1558648B1的权利要求1的轻链和重链CDR区, i),(ii)(a)和(iii)(SEQ ID Nos.16、17、18、13、14和15),特别是包含轻链和重链可变区序列的抗体根据EP1558648B1的权利要求4(SEQ ID Nos.4和2),特别是ofatumumab