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Surgical resection of a solitary liver metastasis from nasopharyngeal carcinoma:a case report

机译:鼻咽癌孤立性肝转移的手术切除1例

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BACKGROUND: Nasopharyngeal carcinoma (NPC) has a propensity to develop distant metastases at a high rate and with poor prognosis. Metastatic sites are usually multifocal and involve bones, lungs, liver and distant lymph nodes. Management of metastatic disease is essentially palliative and is based on chemotherapy. METHODS:A 50-year-old man with a solitary liver metastasis from a newly diagnosed NPC was treated by segmentectomy. Prior to surgery, neoadjuvant chemo-therapy followed by concurrent chemoradiotherapy was administered. RESULTS:Complete remission of the primary disease was achieved, although the size of the hepatic lesion was increased. After resection of the liver metastasis, no signs of local or distant recurrence was noted during the 6-month follow up. CONCLUSION:Although surgical treatment has a limited role in metastatic NPC, there are rare cases of localized disease with a reasonable outcome after resection.
机译:背景:鼻咽癌(NPC)倾向于发生远处转移,预后较差。转移部位通常是多灶性的,涉及骨骼,肺,肝脏和远处的淋巴结。转移性疾病的治疗基本上是姑息性的,是基于化学疗法的。 方法:对一名新诊断的NPC发生单发肝转移的50岁男性进行了节段切除术治疗。在手术之前,先进行新辅助化学疗法,然后进行放化疗。 结果:尽管肝脏病变的大小增加了,但已完全缓解了原发疾病。切除肝转移后,在6个月的随访中未发现局部或远处复发的迹象。 结论:尽管外科手术治疗转移性鼻咽癌的作用有限,但仍有少数病例发生局限性疾病并在切除后具有合理的预后。

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  • 来源
    《国际肝胆胰疾病杂志(英文版)》 |2006年第004期|610-612|共3页
  • 作者单位

    Liver Surgical Unit Delis S, Biliatis I, Dervenis C, and Department of Pathology Bourli A, Agia 0lga General Hospital of Athens, Agias 0lgas 3-5 Street, Athens, Greece, and Department of Molecular Pathology, Mitera Hospital, Athens, Greece Kapranos N;

    Liver Surgical Unit Delis S, Biliatis I, Dervenis C, and Department of Pathology Bourli A, Agia 0lga General Hospital of Athens, Agias 0lgas 3-5 Street, Athens, Greece, and Department of Molecular Pathology, Mitera Hospital, Athens, Greece Kapranos N;

    Liver Surgical Unit Delis S, Biliatis I, Dervenis C, and Department of Pathology Bourli A, Agia 0lga General Hospital of Athens, Agias 0lgas 3-5 Street, Athens, Greece, and Department of Molecular Pathology, Mitera Hospital, Athens, Greece Kapranos N;

    Liver Surgical Unit Delis S, Biliatis I, Dervenis C, and Department of Pathology Bourli A, Agia 0lga General Hospital of Athens, Agias 0lgas 3-5 Street, Athens, Greece, and Department of Molecular Pathology, Mitera Hospital, Athens, Greece Kapranos N;

    Liver Surgical Unit Delis S, Biliatis I, Dervenis C, and Department of Pathology Bourli A, Agia 0lga General Hospital of Athens, Agias 0lgas 3-5 Street, Athens, Greece, and Department of Molecular Pathology, Mitera Hospital, Athens, Greece Kapranos N;

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  • 入库时间 2022-08-19 03:39:25
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