原发性肝癌合并门静脉癌栓的综合介入治疗

摘要

目的:研究原发性肝癌合并门静脉癌栓的患者接受综合介入治疗的临床效果.方法:选取过去我院收治的原发性肝癌合并门静脉癌栓的患者88例,随机将其分为对照组和治疗组,平均每组44例.对照组采用经导管肝动脉化疗栓塞方式进行治疗;治疗组采用经导管肝动脉栓塞联合门静脉化疗综合介入治疗方式进行治疗.比较两组患者在治疗期间出现不良反应例数、肝癌疾病治疗方案实施总时间、原发性肝癌合并门静脉癌栓疾病治疗的总有效率.结果:治疗组患者在治疗期间仅出现17例不良反应,少于对照组的39例,组间差异显著(P<0.05);肝癌疾病治疗方案实施总时间短于对照组,差异显著(P<0.05);原发性肝癌合并门静脉癌栓疾病治疗的总有效率为86.3%,高于对照组的56.8%,组间差异显著(P<0.05).结论:原发性肝癌合并门静脉癌栓的患者接受综合介入治疗,可以有效减少化疗原因所导致的不良反应,缩短疾病的治疗时间,并提高治疗效果.%Objective: To study the clinical effect of comprehensive interventional therapy for patients with primary liver cancer with portal vein tumor thrombus. Methods: 88 patients with primary liver cancer combined with portal vein tumor thrombus admitted to our hospital were randomly divided into the control group and the treatment group, with an average of 44 cases in each group. The control group was treated by transcatheter arterial chemoembolization, and the treatment group was treated by transcatheter arterial chemoembolization combined with portal vein chemotherapy. The total number of adverse reactions, the total time of implementation of liver cancer treatment plan, and the total effective rate of the treatment of primary hepatocellular carcinoma combined with portal vein tumor thrombus were compared between the two groups. Results: The patients in the treatment group were only 17 cases of adverse reactions during the treatment period, less than 39 cases in the control group, significant difference between groups (P<0.05); liver disease treatment scheme to implement the total time shorter than the control group, the difference was significant (P<0.05); primary hepatocellular carcinoma with portal vein tumor thrombus disease treatment total efficiency is 86.3%, higher than 56.8% in the control group, significant difference between groups (P<0.05). Conclusion: Patients with primary hepatocellular carcinoma combined with portal vein tumor thrombus can receive the comprehensive interventional therapy, which can effectively reduce the adverse reactions caused by chemotherapy,shorten the time of disease treatment and improve the therapeutic effect.