醇介质中超声波促进一锅法合成吡喃并2,3-d嘧啶衍生物

摘要

在超声波辐射下,以无水乙醇为溶剂,苯甲醛、丙二腈和巴比妥酸为试剂,合成吡喃并[2,3-d]嘧啶衍生物,并利用正交设计法探索最佳反应条件。%In ultrasonic radiation, with anhydrous alcohol as solvent, benzaldehyde, propylene nitriles and benzodiazepines acid as reagent, synthetic of pyrano [ 2,3 - d ] pyrimidine derivatives, using the orthogonal design method to explore the best reaction conditions.