葛根素药理作用研究进展

摘要

目的：葛根素是从豆科植物野葛中提取分离出的一种单体，属异黄酮类化合物。葛根素药效明确，药理活性强，药理作用广泛。大量实验研究表明，葛根素具有抗心律失常、抗心肌缺血、扩张血管、改善微循环、降血脂、降血糖、增加脑血流量、抗脑缺血-再灌注损伤、保护脑神经细胞、抗氧化、抗酒精中毒、调控骨代谢、降低眼压作用等。现就葛根素的药理作用作如下综述。%Objective:Puerarin is a single genus separated out of Radix Puerariae, isoflavones,it has a variety of pharmacological effects,pharmacological activity,definite efficacy. A lot of experimental research shows that, puerarin has anti-arrhythmic, against my-ocardial ischemia, the dilation of blood vessels, improve microcirculation, fall hematic fat, fall blood sugar, increase cerebral blood flow, anti cerebral ischemia-reperfusion injury, protect brain cells, antioxidant, alcohol poisoning, regulation bone metabolism, reduce intraocular pressure effect, etc. The pharmacological effects of puerarin is summarized as follow.