苏州地区儿科急性下呼吸道感染住院儿童病毒病原学回顾性研究

摘要

目的：确定苏州地区呼吸道病毒在急性下呼吸道感染（ ALRIs）住院儿童中的占比和重要性。方法回顾性研究并收集2013－01～2014－12间在南京医科大学附属苏州医院儿科因急性下呼吸道感染住院儿童的鼻咽部标本433例。使用直接免疫荧光法检测呼吸道合胞病毒（RSV）、腺病毒（ADV）、副流感病毒（PIV）1－3型、流感病毒（flu）A型和B型。结果433例ALRI患儿中，133份标本检测出病毒。 RSV主要见于年龄小于1岁的儿童。秋冬季是病毒发病高峰。结论呼吸道病毒是苏州地区ALRIs儿童重要病原，其约占总病例的30.7％。 RSV是引起病毒性ALRIs最常见的病原，大多数儿童发病年龄小于1岁，且患细支气管炎明显高于肺炎。%Objective To determine the load and importance of respiratory viruses in hospitalized children with acute lower respiratory tract infections(ALRIs) in Suzhou Area.Methods A retrospective study of 433 children with ALRI in the Department of Pediatrics , Suzhou hospital Affiliated to Nanjing Medical University from January , 2013 to December , 2014 was done.Respiratory syncytial virus (RSV),adenovirus(ADV),type 1 to 3 parainfluenza viruses(PIV),and type A and B influenza virus(flu)were detected by direct immuno-fluorescence.Results Of the 433 children with ALRI, viruses were detected in 113 specimens.RSV was common in children under 1 year old.And autumn was the peak of morbidity.Conclusion Respiratory viruses are the important cause of ALRIs in children in Suzhou Are-a, which accounts for 30.7%.The RSV is the most common pathogen causing ALRIs.Most of the children are younger than 1 year old, and are more likely to present with bronchiolitis than pneumonia.