彩色多普勒超声与DSA诊断缺血性脑血管病患者颅外段颈动脉狭窄的对照研究

摘要

Objective:To investigate the values of color doppler flow image ( CDFI ) and digital sub-traction angiography ( DSA) in diagnosing extracranial carotid stenosis in patients with ischemic cerebrovascu-lar disease. Methods:A total of 50 patients with ischemic cerebrovascular disease were selected and examined by CDFI and DSA. With the DSA result as a gold standard, the concordance between the results of the two methods was analyzed. Results:The detectable rates of CDFI and DSA were 84.00% and 76.00% respective-ly, and the difference was statistically insignificant ( P>0.05);and the two methods had insignificantly differ-ent results of degree of carotid stenosis ( P>0.05) . There was good concordance between the degree of carotid stenosis revealed by CDFI and that revealed by DSA ( Kappa value=0.7512, P<0.05) . The sensitivity, speci-ficity, accuracy, positive predictive value, and negative predictive value of CDFI in diagnosis of carotid steno-sis were 88.10%, 87. 50%, 88. 00%, 97. 37%, and 58. 33%, respectively. Conclusion: CDFI is fairly ac-cordant with DSA in detectable rate of carotid stenosis and judgment of the degree of the stenosis, without wound, repeatable, and is applicable to the screening of extracranial carotid stenosis.%目的：：探讨彩色多普勒超声( CDFI)和数字减影血管造影( DSA)在缺血性脑血管病患者颅外段颈动脉狭窄诊断中的价值。方法：选择50例缺血性脑血管病患者,分别行CDFI与DSA检查,以DSA检查结果为金标准,分析二者检查结果的一致性。结果：颈动脉狭窄CDFI检出率84.00％、DSA为76.00％,差异无统计学意义( P>0.05)；两种方法检查显示颈动脉狭窄程度比较,差异无统计学意义( P>0.05)。 CDFI检查显示颈动脉狭窄程度与DSA具有较好的一致性( Kappa值＝0.7512,P<0.05)。 CDFI检查诊断颈动脉的敏感性为88.10％,特异性为87.50％,准确性为88.00％,阳性预测值为97.37％,阴性预测值58.33％。结论：CDFI在颈动脉狭窄检出率及狭窄程度判定与DSA具有较好的一致性,无创伤,可重复好,适合于颅外段颈动脉狭窄的筛查。