彩色多普勒超声监测妊娠高血压综合症对肾脏及子宫胎盘血液循环的影响

摘要

目的:分析彩色多普勒超声监测妊娠高血压综合症(PIH)对孕妇肾脏及子宫胎盘血液循环的影响.方法:将138例P IH患者设为研究组,其中轻度P IH 45例、中度P IH 60例、重度P IH 33例;将62例正常妊娠者设为对照组.比较两组的基本情况,SA、RA、IRA、UT-A、MCA的PI、RI、S/D,孕20～25、26～30、31～35、36～41周的脐静脉血流量.结果:对照组的年龄、孕周、文化程度、经济收入与研究组相比,差异无统计学意义(P>0.05);研究组存在疾病史的患者明显大于对照组,差异有统计学意义(P<0.05).轻度PIH的PI与RI、RA的RI、UT-A的RI、MCA的RI与对照组比较,差异均无统计学意义(P>0.05);中度PIH和重度PIH的SA、RA、IRA、UT-A的PI、RI、S/D明显大于对照组,差异均有统计学意义(P<0.05);研究组中度PIH和重度PIH的MCA的PI、RI、S/D明显小于对照组,差异均有统计学意义(P<0.05).孕20～25周、孕26～30周时,研究组轻度PIH的脐静脉血流量与对照组比较,差异均无统计学意义(P>0.05);孕20～25周时,研究组中度PIH、重度PIH的脐静脉血流量与对照组比较,差异均无统计学意义(P>0.05);孕26～30周、孕31～35周、36～41周时,研究组中度PIH、重度PIH的脐静脉血流量明显大于对照组,差异均有统计学意义(P<0.05).结论:彩色多普勒超声监测能够及时预测妊娠者肾脏及子宫胎盘血液动力学变化,为临床预防和控制P IH的发生发展提供更为科学的敏感指标.%Objective:To analyze the effect of color ultrasound monitoring on blood circulation of kidney and uterus placenta in pregnancy-induced hypertension ( PIH) syndrome. Methods:138 cases of PIH patients were divided into the study group, among which there were 45 cases of mild PIH, 60 cases of moderate PIH and 33 cases of severe PIH;62 cases of normal pregnancy people were selected as the control group. The basic situations such as SA, RA, IRA, UT-A, PI of MCA, RI, S/D, umbilical vein blood flow at 20～25,26～30, 31～35,36～41 weeks during pregnancy of the two groups were compared. Results:The control group's age, gestational weeks, educational level, economic income showed no statistical significance ( P>0.05) with those of the study group;The study group's proportion of patients with disease history was sharply higher than that of the control group, the difference had statistical meaning ( P<0.05) . Distance about PI , RI of RA, RI of UT-A, RI of MCA in the mild PIH and the control group showed no statistical significance ( P>0.05);SA, RA, IRA, PI of UT-A, RI, S/D of the moderate PIH and severe PIH were significantly higher than those of the control group, the differences had statistical significance ( P<0.05); PI of MCA , RI, S/D of the moderate PIH and severe PIH in the study group were significantly smaller than those of the control group, the differ-ences had statistical significance ( P<0.05) . At 20～25 weeks, 26～30 weeks of gestation, compared with the control group, umbilical vein blood flow of the mild PIH of the study group showed no statistical significance ( P>0.05);At 20～25 weeks of gestation, umbilical vein blood flow of moderate PIH, severe PIH of the study group showed no statistical significance (P>0.05) when compared with that of the control group; At 26～30 weeks, 31～35 weeks, 36～41 weeks of gestation, umbilical vein blood flow of moderate PIH, severe PIH of the study group was significantly higher than that of the control group, the differences had statistical signifi-cance ( P<0. 05 ) . Conclusion: Color doppler ultrasound monitoring can be used to predict hemodynamics changes of kidney and uterus placenta in pregnancy, and provide a more sensitive indicator of science for clini-cal prevention and control of occurrence and development of PIH.