首页> 中文期刊> 《河北医学》 >脑梗死患者血清尿酸水平与颈动脉粥样硬化斑块危险因素的相关性分析

脑梗死患者血清尿酸水平与颈动脉粥样硬化斑块危险因素的相关性分析

         

摘要

Objective:For cerebral infarction uric acid level and relationship between risk factors of carotid atherosclerotic plaques were analyzed.Methods:a retrospective analysis of Oct. 2015 to Oct. 2016 in our hospital make a diagnosis and give treatment for cerebral infarction clinical data of 160 patients, according to the inspection result into the stability of carotid ultrasound plaque group, the stability of plaque and plaque group, 66 cases, 40 cases and 54 cases respectively, compare the three groups of uric acid levels, and with the help of double function colour to exceed, nature and intima-media thickness in patients with carotid plaques to detect them.Results:The results of carotid atherosclerotic plaque risk factors including carotid inti-ma-media thickness, uric acid, glycated hemoglobin level, blood sugar 2 hours after meal;Serum uric acid level unstable plaque group were higher than stability of plaque and plaque group ( P < 0.05);Uric acid and carotid intima middle thickness and high density lipoprotein cholesterol negative correlation, and triglycerides appear positive correlation ( P <0.05);Serum uric acid level for cerebral infarction carotid unstable plaque in-dependent risk factors.Conclusion:human serum uric acid level for cerebral infarction carotid atherosclerotic plaque formation risk factors, and as an independent risk factor of stability plaques, according to the uric acid level in patients with clinical and ultrasonic diagnosis implement effective prevention measures, to promote pa-tients to alleviate.%目的:对脑梗死者尿酸水平和颈动脉粥样硬化斑块的危险因素间关系进行分析.方法:回顾性地分析2015年10月至2016年10月本院诊治为脑梗死160例患者临床资料,按照颈动脉超声的检查结果分成非稳定性斑块组、稳定性斑块组及无斑块组,分别为66例、40例及54例,对比三组尿酸水平,且借助双功能彩超对患者颈动脉斑块性质和内膜中层的厚度加以检测.结果:颈动脉粥样硬化斑块的危险因素包括颈动脉内膜中层的厚度、尿酸、糖化血红蛋白水平、餐后2h血糖;非稳定性斑块组血清尿酸水平均比稳定性斑块组和无斑块组高(P<0.05);尿酸和颈动脉内膜的中层厚度与高密度脂蛋白胆固醇呈现负相关性,与甘油三酯呈现正相关性(P<0.05);血清尿酸水平为脑梗死者颈动脉非稳定性斑块独立危险性因素.结论:人体血清尿酸水平为脑梗死者颈动脉粥样硬化斑块形成危险性因素,且为非稳定性斑块形成独立危险性因素,临床可根据患者体内尿酸水平和超声诊断结果实施有效防治举措,促进患者病情缓解.

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