肥胖1号方治疗脾虚痰湿型肥胖症合并胰岛素抵抗疗效观察

摘要

Objective To survey the clinical effect of Feipang Yihao decoction on the treatment of spleen-deficiency and phlegm-turbid stagnation type obesity with insulin resistance Methods 60 cases of spleen-defi-ciency and phlegm -turbid stagnation type obesity with insulin resistance were randomly divided into a treatment group ( treated with Feipang-Yihao Decoction and Metformin) and a control group ( treated with Metformin) ,with 30 cases in each group and performed a therapeutic course for 12 weeks.The clinical efficacy and the change of symptom checklist and BMI,Blood lipid level and HOMA-IR before and after treatment were evaluated.Results After 12 weeks of treatment,BMI,Blood lipid level and HOMA-IR after treatment were obviously improved (P<0.05) as compared with those before treatment in two groups ( P<0.05) .Conclusion Feipang Yihao decoction on spleen-deficiency and phlegm-turbid stagnation type obesity with insulin resistance has safe and reliable curative effect.%目的：观察肥胖1号方治疗脾虚痰湿型肥胖症合并胰岛素抵抗的临床疗效。方法将60例脾虚痰湿型肥胖症合并胰岛素抵抗患者随机分为2组，对照组30例予二甲双胍治疗，治疗组30例在对照组治疗基础上加肥胖1号方。2组均治疗12周后，统计2组治疗前后体质量指数（ BMI ）、胰岛素抵抗指数（HOMA-IR）及血脂变化。结果2组治疗后BMI、HOMA-IR及血脂均较对照组明显改善（P＜0．05）。结论肥胖1号方治疗脾虚痰湿型肥胖症合并胰岛素抵抗疗效确切，安全可靠。