缺乏葡萄糖6磷酸脱氢酶导致新生儿黄疸的特点分析

摘要

Objective:To investigate and analysis of G6PD induced neonatal hyperbilirubinemia characterized by a lack of.Methods:Reviewing the data of 95 cases of neoG natal hyperbilirubinemia,on the detection of G6PD deficiency with jaundice by statistical method analysis and neonatal gender relations,the other to calculate G6PD the lack of correlation with jaundice.Result:95 cases of jaundice in 60 cases for G6PD deficiency,including male G6PD average of(2.9 ± 1.1)U/gHb,significantly lower than the feG male(P<0.05),while the male bilirubin in infants with average level(400.1 ± 35.2)umol/L,(P>0.05)was significantly higher than that in female children,children in viG vo G6PD activity decreased and the level of bilirubin related elevated levels of line(r=-0.91).Conclusion:Mastering the jaundice of newborn G6PD lack of characteristics is of great significance to take effective preventive measures.%目的：探讨与分析葡萄糖6磷酸脱氢酶(G6PD)缺乏致新生儿高胆红素血症发生特点.方法：总结高胆红素血症新生儿95例资料,对检测出的 G6PD 缺乏合并黄疸患儿通过统计学方法分析与新生儿性别关系,另计算 G6PD缺乏与黄疸发生的相关性.结果：95例黄疸患儿中有60例为 G6PD缺乏,其中男性 G6PD 平均水平为(2．9±1．1)U/gHb,明显低于女性(P＜0．05),而男性患儿胆红素平均水平(400．1±35．2)umol/L,明显高于女性患儿(P＞0．05),患儿体内 G6PD 活性降低水平与胆红素升高水平直线相关(r＝-0．91).结论：掌握 G6PD缺乏的新生儿黄疸的特点对于采取有效的预防措施具有重要的意义.