Objective To explore the efficacy of thermotherapy combined with cisplatin in the treatment of old patients with malignant pleural effusion. Methods Forty elderly patients of malignant pleural effusion with chest tightness and shortness of breath were randomly divided into the control group (pleural effusion drainage followed by infusion of 75 mg/m2 cisplatin) and the study group (pleural effusion drainage followed by infusion of 75 mg/m2 cisplatin and then thermotherapy). The absorption of pleural effusion was observed. Results The success rate of thoracen-tesis was 100%. The total effective rate was 90% in the study group and 65% in the control group after treatment, with statistically significant difference between the two groups (P<0.05). No significant abnormal liver and kidney function was found in the two groups. Conclusion Thermotherapy combined with cisplatin after pleural effusion drainage is safe and effective for the treatment of elderly patients with malignant pleural effusion, which is superior than simply infusion of cisplatin.%目的 探讨胸腔注射顺铂联合热疗对老年恶性胸腔积液的疗效.方法 将有胸闷、气促症状的老年恶性胸腔积液患者40例随机分为对照组(胸腔积液引流后,胸腔内注入顺铂75 mg/m2)和实验组(胸腔积液引流后,胸腔内注入顺铂75 mg/m2,并联合热疗),观察胸腔积液吸收变化情况.结果 胸腔穿刺引流术成功率为100％,治疗后评估,实验组20例总有效率为90％,对照组20例总有效率为65％,实验组明显高于对照组(P＜0.05)；两组均无明显肝、肾功能异常.结论 胸腔穿刺引流术后胸腔注入顺铂及热疗对老年恶性胸腔积液患者的治疗安全、有效,比单纯胸腔内注入顺铂更能有效控制恶性胸腔积液.
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