The acute toxicity of m-cresol to juvenile C. carpio was determined to provide a reference for preventing toxicosis of juvenile C. carpio in cultivation stage. The results showed that the fatality rate of juvenile C. carpio exposed in m-cresol solution increased by concentration and time. And showed obvious time-dose effect. LC50(24 h),LC50(48 h) and LC50(72 h) of m-cresol were 32. 33 mg/L (95% confidence interval were 28. 81 - 36. 27 mg/L) ,22. 91 mg/L(95% confidence interval were 20. 93 - 25. 07 mg/L) and 22. 32 mg/L (95% confidence interval were 19. 91 ~ 25. 18 mg/L), respectively, the safe concentration was 2. 23 mg/L. M-cresol belonged to moderate toxic substances.%为防止建鲤幼鱼培育阶段间甲酚的中毒提供参考,研究了间甲酚对建鲤(Cyprinus carpio var.Jian)幼鱼的急性毒性.结果表明:建鲤幼鱼暴露于不同浓度的间甲酚溶液中,其致死率随着间甲酚浓度的增加和时间的延长呈增加趋势,表现出明显的时间-剂量效应.间甲酚24 h的LC50为32.33 mg/L,95％可信限为28.81～36.27 mg/L;48 h的LC50为22.91 mg/L,95％可信限为20.93～25.07 mg/L;72 h的LC50为22.32mg/L,95％可信限为19.91～25.18 mg/L；安全浓度(SC)为2.23 mg/L,属于中等毒性.
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