宫内发育迟缓（IUGR）又称小于胎龄儿（SGA），不仅影响近期健康，且对远期健康和生长发育具有重要影响，成年后2型糖尿病、肥胖、高血压、冠心病等代谢综合征的发病率明显增高。可能的机制是在生命早期个体对不利的刺激高度敏感，产生基因表达的异常，影响内分泌系统，从而对某些器官的结构或功能产生长期或永久性的影响。我们需从做好产前母体的营养与健康管理、小于胎龄儿出生后的系统管理、喂养选择纯母乳喂养等措施减少疾病的发生。%Intrauterine growth retardation (IUGR),also known as the small for gestational age (SGA),not only affects the recent health and has an important influence on long-term health and growth development. They are more easy to get the metabolic syndrome such as adult metabolism of type 2 diabetes,obesity,hypertension,coronary heart disease. Possi-ble mechanism is produced in the early life of individual,is highly sensitive to adverse stimuli gene expression abnormalities which affecting the endocrine system,thus it have a long-term or permanent impact on the structure and function of some or-gans. We need to do more in prenatal maternal nutrition and health management,system management of SGA infants,pure breast feeding. Thus these could reduce the occurrence of metabolic syndrome.
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