Objective To analyze the content of cholinesterase in patients with sepsis and relevance with procalcitonin , to provide a new screening test ensitive indicators for early diagnosis of sepsis .Methods 60 cases of sepsis were selected as the observation group , another 60 cases of non-septic patients were selected as the control group , serum cholinesterase activity of the two groups and the content of PCT in observation group were detected , analysis of the correlation between PCT and cholinesterase .Results The cholinesterase in observation grou was significantly higher than control group , the difference was statistically significant ( P <0.05 ); cholinesterase and procalcitonin showed some linear correlation curve:y=2 325.23 x+239 882.3 ( r=0.843 ) .Conclusion The serum cholinesterase showed some linear correlation with procalcitonin , can be considered for early evaluation and prognosis of sepsis .%目的：分析脓毒症患者胆碱酯酶含量及其与降钙素原的相关性，为早期诊断脓毒症提供一个新的初筛检测敏感性指标。方法选择60例脓毒症患者为观察组，另选择同期非脓毒症患者60例作为对照组，测定两组患者血清胆碱酯酶活性，且测定观察组PCT含量，分析PCT与胆碱酯酶的相关性。结果观察组胆碱酯酶含量明显高于对照组，差异有统计学意义（ P＜0．05）；胆碱酯酶与降钙素原呈现一定线性相关，相关性曲线为： y＝2325．23 x＋239882．3（ r＝0．843）。结论血清胆碱酯酶结果与降钙素原呈现一定线性关系，可考虑用于早期评估脓毒症及预后情况。
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