阿托伐他汀联合缬沙坦对慢性肾炎的临床疗效分析

摘要

Objective To study the clinical efficacy of Atorvastatin Combined with valsartan in the treatment of chronic nephritis.Methods 90 patients with chronic nephritis were randomly divided into two groups in January 2014 to 2016 year in June.The single drug group was treated with valsartan,and the combination group was treated with atorvastatin combined with valsartan.The total effective rate of two groups of patients with chronic nephritis,renal function,diastolic blood pressure and systolic blood pressure before and after treatment were compared.Results Patients with chronic nephritis treated with combined treatment group total efficiency is higher than that of the single drug group,P＜0.05;two groups before the treatment of diastolic blood pressure,renal function,blood pressure showed no significant difference,P＞0.05;after treatment,the combination group renal function,diastolic blood pressure,systolic blood pressure improved more significantly,P＜0.05.Conclusion Atorvastatin combined with valsartan is effective in the treatment of chronic nephritis,can effectively improve the blood pressure and renal function of patients,it is worthy of popularization and application.%目的 研究阿托伐他汀联合缬沙坦对慢性肾炎的临床疗效.方法 以2014年1月-2016年6月慢性肾炎患者90例随机分为两组.单一药物组采用缬沙坦治疗,联合用药组采用阿托伐他汀联合缬沙坦治疗.比较两组患者慢性肾炎治疗总有效率;治疗前和治疗后患者肾功能指标、舒张压、收缩压的差异.结果 联合用药组患者慢性肾炎治疗总有效率高于单一药物组,P＜0.05;治疗前两组肾功能指标、舒张压、收缩压比较无显著差异,P＞0.05;治疗后联合用药组肾功能指标、舒张压、收缩压改善幅度更大,P＜0.05.结论 阿托伐他汀联合缬沙坦对慢性肾炎的临床疗效确切,可有效改善患者血压和肾功能,值得推广应用.