白花蛇舌草不同溶剂提取方法差异成分分析

摘要

High performance liquid chromatography-time of flight mass spectrometry(HPLC- Q-TOF-MS)method was proposed for the analysis different compounds among different solvent extracts. The difference among the ion chromato⁃grams were analyzed by Metabolite Detect Software and identified by chemistry smart formula. The result shows Ursolic ac⁃id/oleanolic acid in Chloroform extracts may lead to the best antitumor activity. This study offer the reference for the rela⁃tive anti-tumor researchs.%文中采用液相色谱质谱联用（HPLC-Q-TOF-MS）技术对白花蛇舌草不同极性萃取物的化学成分进行了分析。不同萃取物的谱图经Metabolite Detect软件分析出谱图间的差异色谱峰后，并通过chemistry smart formula软件推测出了每一个差异色谱峰的化学式。结果显示氯仿提取物中熊果酸/齐墩果酸可能是抗肿瘤的有效成分，该研究为抗肿瘤的相关研究提供参考。