State Key Laboratory of Environmental Aquatic Chemistry Center for Eco-Environmental Sciences Academy of Sciences 100085;
University of Chinese Academy of Sciences 100049;
State Environmental Protection Engineering Center for Harmless Treatment and Resource Utilization of Antibiotic Residues 835007;
Institute for Biomedicine&the Centre for Antibiotic Resistance Research of Gothenburg SE-41346;
Australian Research Council(ARC)Centre of Excellence in Synthetic Biology of Biological Sciences of Science and Engineering University 2109;
Pharmaceutical manufacturing; Resistome; Antibiotic; Risk assessment; Remediation; Land application;