唤醒灯Wake-up Light HF3500/05

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唤醒灯Wake-up Light HF3500/05

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与传统的闹钟不同，这款唤醒灯通过模仿日出的方式，用一种温柔的方式将人自然唤醒。光线强度自然递增直至达到足够唤醒用户的强度。HF3500／05不仅能照明，还有“自然”的闹钟声，甚至还有收音机功能，这些功能统统被结合在了一个明显的圆形造型中。红点奖评委认为，和它的前任一样，这款闹钟的功能性令人信服。其所使用的新技术将其打造得更有吸引力，使其能够成为一件标志性的产品．

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《设计》|2015年第1期|21|共1页
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入库时间 2022-08-17 16:40:13

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1. 科锐全系列LED格栅灯替代灯通过Design-Lights联盟认证 [J] . . 现代显示 . 2011,第010期
2. 自然唤醒更多深度睡眠：欧西亚illumi意境唤醒灯WL2O1 [J] . . 数字家庭 . 2013,第005期
3. 科锐全系列LED格栅灯替代灯通过DesignLights联盟认证 [J] . . 电子设计工程 . 2011,第020期
4. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004）（P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
5. 5～23W小型荧光灯（CFL）电子驱动器VK05CFL及其应用电路 [J] . 杨立新 ,姜宇 . 电子制作 . 2003,第004期
6. 电子游戏背景音乐的唤醒度和愉悦度对生理唤醒和攻击性行为的影响 [C] . 张久林 ,高雪梅 . 中国心理学会心理学教学工作委员会与人格心理学分会2012年学术年会 . 2012
7. Emolight：音乐情感驱动的家用气氛灯效交互设计 [A] . 黄璐敏 . 2019

唤醒灯Wake-up Light HF3500/05

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