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《海岸生命医学杂志(英文版)》
>Chemical composition, antioxidant and antimicrobial activities of the essential oil ofSantolina chamaecyparissus L. of Algeria
Chemical composition, antioxidant and antimicrobial activities of the essential oil ofSantolina chamaecyparissus L. of Algeria
Objective:To investigate the chemical composition, antioxidant and antimicrobial activities of essential oil ofSantolina chamaecyparissus L. cultivated in Algeria. Methods: The chemical composition of hydrodistilled essential oil from flowering aerial parts has been analyzed by gas chromatograph and gas chromatograph-mass spectrometer techniques. The antioxidant activities conducted by 2,2-diphenyl-1-picrylhydrazyl scavenging test andβ-carotene bleaching test. The antimicrobial activity was realised by agar disc diffusion method and cornell medical index was determined by agar dilution method in solid medium. Results:About 36 components accounting more than 82% of the total oil were identified. Oxygenated monoterpenes was the main fraction (54.66%) and was represented by artemisia ketone (40.33%) as major component of this oil. The other major constituents were (Z)-thujone (9.82%), (2Z,6E)-farnesol (7.30%) and limonene (6.87%) and concerning antiradical scavenging test (2,2-diphenyl-1-picrylhydrazyl) had demonstrated a weak activity obtained with an EC50 of (43.01±8.04) and moderate activity forβ-carotene bleaching test (47.00±3.13) at 120 min. In the other hand, this oil was found effective against all tested strains exceptPseudomonas aeruginosa andAspergillusspecies. This activity was ranging from 10 mm to 24 mm with the lowest minimum inhibitory concentration value between under 0.070μg/mL to upper 9μg/mL. Conclusions:The results provided evidence that the studied plant might indeed be potential sources of natural antioxidant and antimicrobial agents.
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