帕金森病个体化诊疗的依从性与疾病进展的相关性分析

摘要

目的：研究个体化诊疗方案的依从性与疾病进展的相关性。方法入组的所有患者在初次就诊时制定帕金森病(PD)的个体化诊疗方案,并要求患者每隔3个月来医院复诊1次,对该患者的个体化治疗方案进行调整。将患者分为3组(第1组：每隔3个月复诊；第2组：每隔6个月复诊；第3组：每隔12个月复诊),患者在初诊时(OM),6个月复诊时(6M),12个月复诊时(12M)应用 Hoehn-Yahr 分级,UPDRS 量表,Schwab 量表对患者进行评分。结果复诊频率不同的3组 Hoehn-Yahr 分级的比较差异无统计学意义(P >0.05)；3组在初诊时的 UPDRS 量表、Schwab 量表的评分与12个月复诊时的评分比较差异有统计学意义(P 0.05).There were significant differences in the rating score evaluated by UPDRS scale and Schwab scale between return visit in the first time and return visit after 12 months among three groups (P < 0.01 ).Conclusion The systematical and normative individual treatment could delay the disease progression,prolong the time of independent activity,improve activities of daily life and the life quality of the patients.