单光子发射计算机断层扫描全身骨显像对多发性骨髓瘤的诊断价值

摘要

Objective To investigate the diagnostic value of single photon emission computed tomography(SPECT) whole body bone scan for multiple myeloma(MM). Methods 50 patients with MM underwent SPECT whole bone scan and X-ray plain examination. Their examination results were performed the comparative analysis. Results Among 207 lesions in 50 cases,the positive detection rates were 80. 2% (166/207) in SPECT whole bone scan and 60. 87% (126/207) in X-ray plain with statistical difference between the two methods(x2 =85. 27 ,P<0. 01). The rib lesion was more sensitive in radionuclide imaging than X-ray (x2=29. 93 ,P <0. 05) ,and skull lesions were more suitable for X-ray examination(x2 =27. 84 ,P<0. 01). Conclusion SPECT whole body bone imaging has higher clinical application value to diagnose MM and monitor its therapeutic efficacy.%目的 探讨单光子发射计算机断层扫描(SPECT)全身骨显像对多发性骨髓瘤(MM)的诊断价值.方法 对50例临床确诊的MM患者行SPECT及X线平片检查,将二者检测结果进行对比分析.结果 50例患者共207个病灶中,SPECT阳性检出率为80.19%,X线平片阳性检出率为60.87%,两种检查方法的检测结果比较,差异有统计学意义(χ2=85.27,P＜0.01).核素显像对肋骨病灶的显示较X线更敏感(χ2=29.93,P<0.05),而颅骨病变则更适合行X线检查(χ2=27.84,P<0.01).结论 SPECT全身骨显像对MM的诊断及疗效的监测具有较高的临床应用价值.