Objective To explore the feasibility and effectiveness of tracing sentinel lymph node(SLN) in endometrial neoplasms using nano-activated carbon. Methods 42 patients with endometrial neoplasm who had accepted surgical treatment were enrolled. Midpoint of anterior wall,bottom and posterior wall of uterine were served as injection points,and the tracer nano-activated carbon were injected into subserosa of uterine to trace and identify the first black-stained lymph nodes during the operation. All lymph nodes removed were submitted to routine pathological testing after operation. Results Uterine serosa were found to be black-stained first in all 42 patients,followed by lymph vessels stained in bilateral pelvic funnel ligament. Among them,lymph vessels in pelvic cavity stained simultaneously in 31 cases(73. 8%). SLNs were identified in 30 patients with a total number of 114. Lymphatic metastasis was occurred in 4 cases(9. 5%) ,3 of them were SLN metastasis,and one of them with abdominal para-aortic lymph node metastasis demonstrated no SLN metastasis. Conclusion Nano-activated carbon tracing for SLN in endometrial neoplasm is feasibility and effectiveness,and has reference value for estimating lymphatic metastasis of endometrial neoplasm.%目的 探讨纳米活性炭示踪子宫内膜癌前哨淋巴结(SLN)的可行性及有效性.方法 选择接受手术治疗的子宫内膜癌患者42例,术中选择子宫前壁、底部及后壁中点作为注射点,将示踪剂纳米活性炭注射于子宫浆膜下,追踪识别最先黑染的淋巴结.术后常规病理检测所有切除的淋巴结.结果 42例患者均首先在子宫浆膜面出现黑染,随后双侧骨盆漏斗韧带内的淋巴管着色,其中,31例(73.8%)患者盆腔内淋巴管同时着色,有30例患者识别出SLN,共计114枚.4例(9.5%)患者发生淋巴结转移,其中3例SLN转移,1例腹主动脉旁淋巴结转移患者的SLN无转移.结论 采用纳米活性炭示踪子宫内膜癌SLN具有可行性及有效性,对子宫内膜癌淋巴结转移的判断有一定参考价值.
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