Objective To explore the effect of electronic antiemetic acupuncture in combination with palonosetron in preven‐ting tardive vomiting induced by highly emetogenic chemotherapy for cancer patients .Methods One hundred and twenty cancer pa‐tients undergoing highly emetogenic chemotherapy were divided into observation group and control group(n=60) .The observation group was treated with electronic antiemetic acupuncture in combination with palonosetron and the control group was treated with palonosetron .The different effects against nausea and vomiting between these two groups were evaluated after 24 hours of the chemotherapy .Results Response rate of improvement of nausea for the observation group and control group from the 2nd day to the 8th day were 90 .0% vs 71 .7% ,68 .3% vs 41 .7% ,60 .0% vs 36 .7% ,65 .0% vs 40 .0% ,80 .0% vs 58 .3% ,91 .7% vs 81 .7% , 98 .3% vs 96 .6% .From the 2nd day to the 6th day there were statistical difference of the two groups(P<0 .05) in the prevention of nausea and from the 7th day to the 8th day ,there was no significantly difference between the two groups(P>0 .05) .Response rate of prevention of vomit for the observation group and control group from the 2nd day to the 6th day were 98 .3% vs 88 .3% , 81 .7% vs 65 .0% ,75 .0% vs 51 .7% ,90 .0% vs 70 .0% ,98 .3% vs 88 .3% ,and there were statistical difference of the two groups (P<0 .05) .The prevention of vomiting in the 7th day and 8th day of the two groups were 98 .3% vs 86 .7% ,98 .3% vs 88 .3% , there were also statistical difference(P<0 .05) .Conclusion The treatment of electronic antiemetic acupuncture in combination with palonosetron have greater effect in prevention of tardive vomiting than palonosetron caused by highly emetogenic chemotherapy .It can be used conventionally in the chemotherapy .%目的：观察电子止吐仪联合盐酸帕洛诺司琼预防高致吐化疗药物所致延迟性呕吐的疗效。方法将120例接受高致吐化疗药物治疗的恶性肿瘤患者分组，试验组（60例）应用电子止吐仪联合盐酸帕洛诺司琼治疗，对照组（60例）应用盐酸帕洛诺司琼治疗。观察和记录两组患者自化疗结束24 h后恶心、呕吐的控制情况。结果试验组和对照组在第2～8天恶心控制有效率分别为90．0％和71．7％、68．3％和41．7％、60．0％和36．7％、65．0％和40．0％、80．0％和58．3％、91．7％和81．7％、98．3％和96．6％。恶心控制情况第2～6天比较差异有统计学意义（P＜0．05），第7、8天比较差异无统计学意义（P＞0．05）。试验组和对照组第2～6天呕吐控制有效率分别为98．3％和88．3％、81．7％和65．0％、75．0％和51．7％、90．0％和70．0％、98．3％和88．3％，差异有统计学意义（ P＜0．05）；第7、8天呕吐的完全控制率分别为98．3％和86．7％、98．3％和88．3％，差异有统计学意义（P＜0．05）。结论电子止吐仪联合盐酸帕洛诺司琼预防高致吐化疗药物所致延迟性呕吐优于单用盐酸帕洛诺司琼，可作为防治高致吐化疗药物所致延迟性呕吐的常规措施。
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