氨溴特罗联合肝素雾化吸入佐治小儿肺炎支原体肺炎疗效观察

摘要

Objective To evaluate the clinical effect of ambroxol and clenbuterol oral solution and at-omized heparin in the treatment of mycoplasma pneumonia.Methods A total of 136 patients with mycoplas-ma pneumonia treated in our hospital from November 201 1 to November 2013 were collected.They were di-vided into two groups randomly,with 68 patients in each group.The patients in both groups received tradi-tional anti-mycoplasma and comprehensive treatment for two courses,and ambroxol and clenbuterol oral so-lution was used for 7 days and atomized heparin for 4 to 7 days for patients in the observation group.The time for the symptoms to disappear,hospital stay,the clinical effect and side effects were observed. Results The total effective rate of observation group was 97.1%(66/68)which was remarkably higher than that in the control group,which was 88.2% (60/68 ),and the difference was statistically significant(P <0.05).The time for cough,moist rales and fever to disappear and hospital stay in the observation group is much less than those in the control group.All the differences were statistically significant(P <0.05).Neither of the groups showed clear side effects.Conclusion The treatment for mycoplasma pneumonia with ambrox-ol and clenbuterol oral solution and atomized heparin is effective,safe and convenient.%目的：观察氨溴特罗口服液联合肝素雾化吸入治疗小儿肺炎支原体肺炎的疗效。方法解放军北京军区第二八一医院儿科2011年11月至2013年11月收治肺炎支原体肺炎患儿136例,随机分为观察组和对照组各68例。对照组采用抗支原体及综合治疗,观察组在对照组治疗基础上加用氨溴特罗口服液、肝素气动雾化吸入治疗。抗支原体治疗2个疗程,氨溴特罗口服液治疗7 d,肝素气动雾化吸入治疗4~7 d。观察治疗后症状体征消失时间、住院时间、疗效及不良反应。结果观察组总有效率为97.1%(66/68),高于对照组88.2%(60/68),差异有统计学意义(P <0.05)。观察组在改善患儿咳嗽、咳痰、肺部哮鸣音及湿啰音消失时间、退热时间及住院时间均低于对照组,差异有统计学意义(P <0.05)。两组治疗中均未发现明显副反应。结论氨溴特罗口服液联合肝素气动雾化吸入佐治小儿肺炎支原体肺炎有明显疗效,安全方便。