锥束X线发光断层成像/CT同步成像控制系统实现

摘要

目的:设计并实现锥束X线激发光学断层成像(cone beam X-ray luminescence CT,CB-XLCT)/CT双模同步成像控制系统,为CB-XLCT小动物活体成像研究提供软件控制平台.方法:基于实验室现有的CB-XLCT/CT系统,利用Microsoft Visual Studio 2010平台,使用多线程编程技术和动态链接库,搭建软件控制平台,实现双模数据的同步采集.通过设计仿体实验,联合CT稀疏角度重建算法,对系统成像性能进行评价.结果:仿体实验结果表明该系统同步成像控制比非同步成像采集时间缩短79％,且成像质量完全可以满足实际需求.结论:CB-XLCT/CT同步成像控制系统有利于CB-XLCT在体研究的开展.%Objective To design and implement a synchronous imaging control system for two modes of cone beam X-ray luminescence CT (CB-XLCT) and CT to provide a software control platform for small animal in vivo imaging.Methods The software control platform was developed with the existing CB-XLCT/CT system,Microsoft Visual Studio 2010 platform,multi thread programming technology and dynamic link library so as to realize synchronous acquisition of two-mode data.The performances of the system imaging were evaluated by designing phantom experiments combined with sparse-view CT reconstruction algorithm.Results The phantom experiments results showed that synchronous imaging control had the acquisition time decreased by 79％ when compared with non-synchronous imaging,and the requirements were met for imaging quality.Conchusion Synchronous imaging control of CB-XLCT/CT facilitates in vivo researches for small animals.