定量组织速度成像测量Tei指数早期评价酒精性心肌损害左室功能的价值

摘要

目的 通过定量组织速度成像(QTVI)测量左心室Tei指数评价酒精性心肌损害早期左室功能变化.方法 86例饮酒者分为三组:B组(31例,每日饮白酒≥90 g或啤酒2～3瓶,每周3～5 d,5～8年),C组(34例,同B组,9～20年),D组(21例,每日饮白酒≥150 g或啤酒4瓶,每周6～7 d,10年以上,饮酒量符合酒精性心肌病诊断标准),A组(正常对照组)40例.对4组进行常规超声参数测定及QTVI参数测定计算Tei指数.结果 常规各超声参数B组与A组间差异无统计学意义(P＞0.05).C组左室舒张末期内径(LVDd)、左室收缩末期内径(LVDs)、舒张末期室间隔厚度(IVSTd)、舒张末期左室后壁厚度(PWTd)、左室射血分数(LVEF)与A组及B组间差异无统计学意义(P＞0.05),舒张功能参数E/A与A组及B组间差异有统计学意义(P＜0.01),D组常规各超声参数与A组、B组和C组间差异有显著性统计学意义(P＜0.01).Tei指数:A组与B组差异无统计学意义(P＞0.05),C组与A组和B组间差异有统计学意义(P＜0.05),D组与A组和B组间差异有显著统计学意义(P＜0.01),D组与C组间差异有统计学意义(P＜0.05).结论 QTVI技术测定Tei指数可作为评价酒精性心肌损害早期左室功能变化的手段之一.%Objective To evaluate left ventricular function in early alcohol-induced myocardial damage by quantitative tissue velocity imaging(QTVI)to detectTeiindex.Methods 86 chronic alcohol abusers were divided into three groups,with group B(more than 90 g ethanol or 2 to 3 bottles of beer daily for 5～8 years,3～5 days per week,n=31) ,group C(more than 90 g ethanol or 2 to 3 bottles of beer daily for 9～20 years,3～5 days per week, n = 34 ) and group D(more than 150 g ethanol or 4 bottles of beer daily for 10 years or more,6 to 7 days per week,n = 21),and group A(the control group, n = 40).The parameters of the conventional echocardiographic andTeiindexes were obtained by using QTVI.Results The conventional echocardiographic parameters and Teiindex showed no significant difference between group A and B(P＞0.05).The conventional echocardiographic parameters showed no significant difference between group C,A and B(P＞0.05) ,but E/A showed significant difference between group A and B(P＜0.01 ),Tei index showed significant difference between group B and C(P＜0.05 ), group A and C(P＜0.05).The conventional echocardiographic parameters andTeiindex showed significant difference between group D and group A, B, C (P＜0.05 or P＜0.01).Conclusions Tei index of left ventricular function by QTVI is valuable in assessing early alcohol-induced myocardial damage.