Objective To investigate qualitative value of virtual tough tissues quantification (VTQ) of focal hypoechoic lesions in fatty liver. Methods Totally 106 lesions in fatty liver in 86 patients were examined using both conventional sonography and VTQ. Results There was significant difference of share wave velocity between malignant group and benign group(P<0. 05). There was no significant difference of share wave velocity between primary hepatic malignant tumors and metastatic liver tumors(P>0. 05). For the discrimination of malignant versus benign hypoechoic lesions in fatty livers, receiver operating characteristic analysis revealed a significant improvement in this discrimination. For the discrimination of malignant versus benign liver lesions, with a cut-off value of 2 m/s for share wave velocity, VTQ improved sensitivity from 45. 45% to 95. 45% , specificity from 75. 61% to 96. 87% arid accuracy from 67. 92% to 96. 36% compared with conventional sonography. Conclusions With VTQ,characterization and diagnostic performance of hypoechoic liver lesions in fatty liver are greatly improved.%目的 探讨声触诊组织量化技术对脂肪肝内低回声病变的定性诊断价值.方法 应用常规超声与声触诊组织量化技术对106个脂肪肝内低回声病变进行检查,对检查结果进行对比分析,鉴别诊断其良、恶性.结果 肝细胞性肝癌、肝转移癌及肝良性病变剪切波速分别为(2.31±1.09)、(2.42±1.18)、(1.35±0.87) m/s,肝细胞性肝癌、肝转移癌组与肝良性病变组剪切波速比较差异均有统计学意义(P＜0.05),肝细胞性肝癌与肝转移癌剪切波速比较差异无统计学意义(P＞0.05).脂肪肝内的低回声病变常规超声鉴别恶性病变的敏感度、特异度、准确率分别为45.45％ (20/44)、75.61％ (62/82)、67.92％ (72/106),以2 m/s作为恶性病变的诊断标准,声触诊组织量化技术鉴别恶性病变的敏感度、特异度、准确率分别为95.45％ (42/44)、96.87％ (62/64)、96.36％ (102/106).结论 声触诊组织量化技术可显著提高脂肪肝内低回声病变的定性诊断效能.
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