A simple and efficient method for the synthesis of novel furo[3,2-c]quinolinone derivatives was developed by a domino nucleophilic/cyclization/elimination reaction in H2O of 3-bromoacetyl-4-hydroxy-1-methylquinolin-2-one with aryl aldehydes, in the presence of 1,4-diazabicyclo[2.2.2]octane(DABCO).The structures were characterized by 1H NMR, 13C NMR, IR, MS(ESI) and elemental analysis.%在1,4-二氮杂二环[2.2.2]辛烷(DABCO)促进下,以水为反应介质,通过3-溴乙酰基-4-羟基-1-甲基-2-喹啉酮与芳香醛的亲核取代、分子内环化及消除的串联反应,合成了9个新型的呋喃并[3,2-c]喹啉酮类化合物,其结构经1H NMR, 13C NMR, IR, MS(ESI)和元素分析表征.
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