经尿道前列腺切除术后泌尿系感染的危险因素分析及防治措施

摘要

目的:探讨经尿道前列腺切除术后泌尿系感染的危险因素及防治措施.方法:回顾性分析70例行经尿道前列腺切除术的患者,术后泌尿系感染的发生情况,并采用单因素分析和多因素Logistic回归分析,分析术后泌尿系感染的相关因素.结果:单因素分析结果表明术前合并糖尿病、术前行导尿术、前列腺体积较大、手术时间较长、术后保留导尿时间较长等使术后泌尿系感染的几率增大(P<0.05),术前预防性应用抗生素可降低术后感染的发生率(P<0.05).多因素Logistic回归分析结果显示:合并糖尿病、术前导尿、前列腺体积>50 mL、手术时间>60 min、术后保留导尿>7 d、术前未预防性应用抗生素是术后并发泌尿系感染的危险因素(P<0.05).结论:术前合并糖尿病、术前导尿、前列腺体积>50 mL、手术时间>60 min、术后保留导尿>7d、术前未预防性应用抗生素是经尿道前列腺切除术后泌尿系感染的危险因素.%Objective To investigate the risk factors and prevention of urinary tract infection after transure-thral prostate resection. Methods Seventy patients treated by transurethral prostate resection with postopera-tive urinary tract infection were analyzed retrospectively. Then single factor analysis and multi-factor logistic re-gression analysis were used to analyze the related factors of urinary tract infection after surgery. Results Sin-gle factor analysis found that preoperative combined with diabetes, preoperative catheterization, larger prostate volume , longer operation time, postoperative retained catheter for a long time could increase the risk of urinary tract infection after operation(P<0.05). Preoperative preventive application of antibiotics could reduce the inci-dence of postoperative infection (P<0.05). Multivariate logistic regression analysis suggested that the combined diabetes, preoperative catheterization, prostate volume over 50 mL, operation time more than 60 min, postopera-tive retained catheter more than 7 d, and no preventive use of antibiotics before surgery were risk factors for post-operative urinary tract infection (P<0.05). Conclusion Combination of diabetes, preoperative catheteriza-tion, prostate volume over 50 mL, operation time more than 60 min, postoperative retained catheter more than 7 d, and no preventive use of antibiotics before surgery are risk factors for urinary tract infection after transurethral prostate resection.