艾滋病患者抗病毒治疗依从性现状及其生命质量影响因素的回归分析

摘要

Objectives Explore antiretroviral treatment adherence and quality of life, as well as its influence factors. Methods A cross-sectional survey research,which applied demographic scale, WHOQOL-HIV-BRIEF, Medication compliance scale to collect information and used SPSS 13. 0 to analysis the data. Results 104 valid questionnaires were received. In this group, the average of medication adherence was 96. 38%, among which compliance well accounted for 89. 42% ;Compared with Chinese norm, quality of life among HIV/AIDS had a lower score except spirituality(P<0. 01) ; Patients with good adherence had a better quality of life, and had a significant difference in independence and environment domains(P<0. 05); In addition, age, income, occupation, infection, CD4+ cell count and hospitalized were relevant with quality of life. Conclusions Medication adherence have already risen in some degree, but still have a low quality of life. To achieve treatment goal and effect, government should carry out comprehensive interventions.%目的 探讨接受抗病毒治疗的艾滋病患者服药依从性与生命质量现状以及相关影响因素.方法 运用横断面调查研究,采用人口学问卷、WHOQOL-HIV-BRIEF中文简表、服药依从性量表收集信息,运用SPSS 13.0统计软件进行数据的分析.结果 收回有效问卷104份.抗病毒治疗患者平均服药依从性为96.38%,其中依从性好的患者占89.42%;调查对象生命质量除精神支柱/个人信仰维度外,均低于常模,差异具有统计学意义(P＜0.01);依从性好的患者生命质量各领域得分均较高,并且在独立性和环境领域差异具有统计学意义(P＜0.05);年龄、月收入、职业、感染途径、CD4+细胞计数及是否因HIV/AIDS住过院均与生命质量相关(P＜0.05).结论 艾滋病抗病毒治疗患者服药依从性已有一定程度的提高,但其生命质量仍偏低,为达到抗病毒治疗效果和目标,需采取综合干预和关怀措施.