Phase Transfer Catalyzed Synthesis under Ultrasonic Irradiation and Bioactivity of N'-(4,6-Disubstituted-pyrimidin-2-yl)-N-(5-aryl-2-furoyl) Thiourea Derivatives

摘要

@@ Acylthiourea derivatives are useful as pesticides, herbicides, fungicides and regulator for plant growth, and also as important intermediates in the organic synthesis. In recent years, phase transfer catalysis reaction technique has been widely recognized as an efficient synthetic tool and attracted much attention. In view of these observations, a series of 5-aryl-2-furoyl thioureas containing substituted pyrimidine ring were synthesized using PEG-400 as solid-liquid phase transfer catalyst under ultrasonic irradiation. All of the new compounds have been exactly determined by IR, 1H NMRand elemental analysis.