纤维蛋白原联合肌钙蛋白 T 评估冠脉狭窄程度价值探讨

摘要

Objective To explore the correlation between the the levels of fibrinogen and troponin T and the severity of coronary artery stenosis .Methods Five hundred patients were collected and were diagnosed with coronary heart diseases by coronary angiography , and the degree of coronary stenosis was evaluated by Gensini score .The lev-els of fibrinogen and troponin T were detected in all the patients .Single factor analysis was performed and the correla-tion between the levels of fibrinogen , troponin T and the degree of stenosis of coronary artery stenosis was analyzed . Results With the increase of Gensini score , the levels of fibrinogen and troponin T increased gradually , and the cor-relation coefficient was 0.638 ( P<0.01 ) .Conclusion Both fibrinogen and troponin T are closely related to the de-gree of coronary stenosis .The combination of fibrinogen and troponin T is significant to evaluate the degree of coro -nary lesions .%目的：探讨纤维蛋白原、血清肌钙蛋白T水平与冠脉狭窄程度的相关性。方法选择经冠脉造影确诊为冠心病的患者500例，以Gensini积分法评价冠脉狭窄程度。检测所有患者的纤维蛋白原及血清肌钙蛋白T水平，并分别对纤维蛋白原浓度、肌钙蛋白T水平及与冠脉病变狭窄程度进行单因素方差分析及相关性分析。结果随着Gensini积分的升高，纤维蛋白原、血清肌钙蛋白T水平逐渐升高，且二者呈正相关，相关系数为0．638，P＜0．01。结论纤维蛋白原、肌钙蛋白T与冠脉狭窄程度密切相关，两者联合检测对临床评估冠脉病变有一定的临床意义。