低舒张压的单纯收缩期高血压研究新进展

摘要

Some elderly hypertensive patients may manifest as diastolic blood pressure (DBP) lower than 60mmHg, a phenomenon known as isolated systolic hypertension (ISH) with low diastolic pressure. More and more evidence shows that DBP<70mmHg is detrimental to the body. What’s more, the ISH patients with lower DBP often have more risk factors and are of higher risk for cardiovascular events, which become a difficulty for the treatment of the elderly hypertension. Nitrates may be a good option.%在有些高龄患者中，会出现舒张压（DBP）＜60mmHg高血压患者，即低DBP的单纯收缩期高血压（ISH）。越来越多的证据表明DBP＜70mmHg对机体是不利的，而低DBP的ISH患者常具有更多的心血管危险因素和更多的心血管事件风险，成为老年高血压降压治疗的难点，使用硝酸酯类药物进行治疗可能是一个有益的选择。