目的：以开放性手术为对照，探讨超声引导下微创经皮肾穿刺取石术治疗孤立肾多发结石的临床疗效。方法：58例泌尿外科病房孤立肾并发多发结石患者随机分组，研究组29例应用超声引导下微创经皮肾穿刺取石术治疗，对照组29例应用开放式取石手术治疗。结果：研究组术中出血量明显少于对照组，术后取净率、术后2个月排净率明显高于对照组，并发症发生率明显低于对照组，两组数据比较差异具有统计学意义(P<0.05)；两组患者手术时间无统计学意义(P>0.05)。两组术后与术前比较、术后2个月与术前比较血肌酐水平差异均无统计学意义，两组间各阶段血肌酐水平差异无统计学意义(P>0.05)。结论：超声引导下经皮肾穿刺取石术治疗孤立肾多发结石具有创伤小、手术出血量少、并发症少、结石取净率和排净率高，手术疗效好，安全性高，适合于临床广泛应用。%Objective:To open operation as control, to investigate the clinical efficacy of ultrasound-guided minimally invasive percutaneous nephrolithotomy in treatment of solitary kidney and multiple calculi. Methods:58 cases of Department of urology ward solitary kidney complicated with multiple stones were randomly divided into two groups, study group 29 cases of application of ultrasound guided minimally invasive percutaneous nephrolithotomy in treatment, 29 cases in the control group open stone operation treatment. Results:The hemorrhage group was significantly less than that of the control group, after the net rate, after 2 months of discharge rate were higher than the control group, the complication rate was significantly lower than the control group, statistically significant differences between the two groups of data (P<0.05);two groups of patients with operation time had no statistical significance (P>0.05). The two groups after operation compared with those before operation, 2 months postoperatively compared with the preoperative serum creatinine levels were not statistically significant, no statistical significance in each stage of blood creatinine level difference between the two groups (P>0.05).Conclusion:Ultrasound guided percutaneous nephrolithotomy in treatment of multiple stones with less trauma, less bleeding, less complications, operation, stone clearance rate and the net rate of solitary kidney operation, good curative effect, high safety, suitable for clinical application.
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