Purpose To summarize the imaging features of inflammatory bowel diseases (IBD) with double-filling method using multi-slice CT enterography (MSCTE), and to evaluate the clinical significance of MSCTE in diagnosis of IBD. Materials and Methods MSCTE data with double-filling method of 52 patients with IBD were retrospectively analyzed. 52 IBD patients included 42 cases of Crohn's disease (CD) and 10 cases of ulcerative colitis (UC). Bowel dilatation and lesions display were evaluated. Results Among 52 patients, ileum dilated optimal in 10 cases (19.23%) and good in 42 cases (80.77%); jejunum dilated good in 21 cases (40.38%) and poor in 31cases (59.62%). Exhaustive evaluation for large bowel diseases were good in 50 cases (96.15%). The ileocecal junction displayed well in 52 cases (100.00%). Among the 42 cases of CD, 20 cases (47.62%) had lesions limited in the small intestine, 22 cases (52.38%) had lesions involved both small intestine and colon. Among 10 cases of UC, 9 cases had lesions limited in the colon, and 1 case with the terminal ileum and the colon involved simultaneously. The MSCTE findings of 52 patients included bowel wall thickening and abnormal enhancement in 52 cases, stenosis in 28 cases, increased mesenteric vascularity in 46 cases, enlarged mesenteric lymph nodes in 27 cases, phlegmon in 10 cases, incomplete intestinal obstruction in 4 cases, abscess or inflammatory masses in 7 cases, fistulas in 3 cases, perianal lesion in 12 cases, serous cavity effusion in 15 cases, sacroiliitis in 13 cases, the urinary and biliary stones in 18 cases, and hepatosplenomegaly in 9 cases. Conclusion MSCTE with double-filling method can delineate the wall lesions of small bowels and colons very well, and can also display extraintestinal lesions and complications. It obviously improves the accuracy of localization and qualitative diagnosis on IBD.%目的：总结炎症性肠病（IBD）在大小肠双充盈法多层螺旋CT（MSCT）肠道成像中的影像表现，评价该成像方法对IBD的诊断价值。资料与方法回顾性分析42例克罗恩病（CD）和10例溃疡性结肠炎（UC）患者的CT资料，均采用大小肠双充盈法MSCT肠道成像，评价肠管扩张程度和病变显示情况。结果52例患者中，回肠扩张最佳10例（19.23%），扩张良好42例（80.77%）；空肠扩张良好21例（40.38%），扩张欠佳31例（59.62%）；大肠评价范围全面50例（96.15%），回盲部显示良好52例（100.00%）。42例CD患者中，仅小肠受累20例（47.62%），大小肠同时受累22例（52.38%）。9例UC仅累及结肠，1例累及全结肠及末端回肠。52例患者的MSCT表现显示明确，其中肠壁增厚及异常强化52例；肠腔狭窄28例，肠系膜血管增多46例，肠系膜淋巴结肿大27例，肠管周围蜂窝织炎10例，不全小肠梗阻4例，脓肿或炎性肿块7例，腹腔内瘘3例，肛周病变12例；浆膜腔积液15例，骶髂关节炎13例，泌尿系及胆系结石18例，肝脾肿大9例。结论大小肠双充盈法MSCT肠道成像不但能较好地同时显示小肠和大肠自身的肠壁病变，而且能明确显示肠外病变及并发症，可以明显提高IBD病变的定位及定性准确率。
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