Objective Comparing with traditional teaching methods of oral histopathology, to probe whether the interactive teaching system of the digital microscope can improve the teaching effi-ciency of experiment of oral histopathology courses. Methods The subjects were the 2010 grade students (40 students) and the 2011 grade students (38 students) majoring in stomatology of South Medical University, and they were evenly divided into 2 groups at random. In the first part of the ex-periment of Grade 2010, the teaching of traditional optical microscope was used in a group of experi-mental courses, and interactive teaching with digital microscope was used in the other group. In the second part of the experiment the two groups swapped the teaching method. While in the whole exper-iment of Grade 2011, traditional optical microscopes were adopted in one group, and in contrast, the interactive teaching system of the digital microscope was adopted in the other group. The P values of the 5 indexes were less than 0.05. After the courses, the 2010 grade students received the questionnaire survey and the 2011 grade students received the quiz about the experimental course, and then the evaluation results of the two groups were compared for t inspection, using SPSS software t test. Result The questionnaire results of Grade 2010 showed that the scores of digital microscope interactive group were higher than those of traditional teaching group in satisfaction with teaching , teacher-student interaction, classroom atmosphere active degree, learning interest, and the understanding of the teach-ing content. The experiment course content test results of Grade 2011 showed that the digital interactive group students averaged 46.26, while the average score of the traditional teaching group was 42.78%. The difference between the two groups had statistical significance, P=0.001. Conclusion Compared with the traditional teaching methods, the interactive teaching system of the digital microscope can enhance the academic grades, improve the teaching efficiency of experiment of oral histopathology courses, and elevate the teaching quality.%目的：探讨与传统口腔组织病理教学方式相比，数码显微互动教学系统是否可以提高口腔组织病理学实验教学效果。方法以南方医科大学2010级（40人）、2011级（38人）口腔医学专业学生为研究对象，将各级学生随机平均分为2组。2010级第一部分实验课其中一组采用传统光学显微镜教学，另一组采用数码显微互动教学；第二部分实验课两组互换。2011级全部实验课程其中一组采用传统光学显微镜，另外一组采用数码显微互动教学。课后2010级学生采用统一的问卷调查，2011级学生采用实验课内容测验的方式对教学效果进行评价。对比两组学生各项结果，利用SPSS软件行t检验。结果2010级学生的问卷调查结果显示，数码显微互动组在教学满意度、师生互动、课堂气氛活跃度、学习兴趣、对教学内容的理解方面的得分均高于传统教学组，5项指标统计分析P值均小于0.05。2011级实验课内容测验结果显示，数码互动组学生成绩平均为46.26分，传统教学组平均成绩为42.78分，两组比较差异具有统计学意义（P=0.001）。结论与传统教学模式相比，数码显微互动教学系统可以提高学生学习成绩，改善口腔组织病理实验课教学效果，提升教学质量。
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