舒脑欣滴丸辅助治疗对脑梗死后头痛症状的疗效观察

摘要

Objective To observe the clinical curative effect of Shunaoxin pil s for treating headache after cerebral infarction.Methods Sixty six patients with cerebral infarction in our hospital from 2013 to 2015 were randomly divided into experimental group (group A)and control group (group B),33 cases in each group.The group B was treated with drugs which control blood pressure,blood glu-cose.Group A was to give Shunaoxin pil s for 3 months in a row on the basis of group B.Then two groups of patients with headache, blood coagulation function test,transcranial Doppler TCD blood flow velocity detection,clinical efficacy and adverse reactions were observed.Results The first 2 week,VAS score was (3.6± 1.3 vs 4.1± 1.6),HIT 6 score was (53.9± 5.8 vs 58.1± 6.1),the total ef-fective rate (75.76% vs 66.66%)in two groups(P<0.05).After of 4 weeks,VAS score (0.9± 0.5 vs 1.9± 0.9),HIT 6 score (42.2± 8.1 vs 47.8± 7.7),P<0.05 (87.88% vs78.79%),group A has prolonged APTT,increased cerebral blood flow velocity than group B (P<0.05).Conclusion Shunaoxin pil can improve headache after cerebral infarction.%目的：观察舒脑欣滴丸辅助治疗对脑梗死后头痛症状的治疗效果。方法将2013年—2015年收治于本院的66例脑梗死后头痛病人,根据随机数字表法分为试验组(A组)、对照组(B组),各33例。B组给予控制血压、血糖、抗血小板等常规治疗；A组在 B组的基础上,给予舒脑欣滴丸口服,3次/天,4丸/次,连续4周；观察两组病人的头痛程度、凝血功能、脑血流速度检测、临床疗效及不良反应。结果治疗2周时,两组头疼程度(VAS)评分(3.6 vs 4.1)、HIT 6评分(53.9±5.8 vs 58.1±6.1)、总有效率(75.76%vs 66.66%)比较有统计学意义(P<0.05)；治疗4周时,两组VAS评分(0.9 vs 1.9)、HIT 6评分(42.2±8.1 vs 47.8±7.7)、总有效率(87.88% vs 78.79%)比较有统计学意义(P<0.05)；A组部分凝血活酶时间(APTT)较 B组延长(P<0.05)；A组脑血流速度较 B组有所提升(P<0.05)。结论随着治疗时间延长,舒脑欣滴丸辅助治疗可以改善脑梗死后头痛症状。