睾丸生殖细胞肿瘤患者行睾丸部分切除术的1、3、5年生存率分析

摘要

目的：分析睾丸生殖细胞肿瘤患者行睾丸部分切除术后的1、3、5年生存率。方法：运用回顾性分析的方法1998年10月至2008年10月110例来我院行睾丸部分切除术的睾丸生殖细胞肿瘤患者的临床资料，分析不同病理类型、术后行不同辅助治疗方式患者的1、3、5年生存率。结果：本研究中110例睾丸生殖细胞肿瘤患者行部分切除术后1年生存率为99.8％，3年生存率为92.8％，5年生存率为87.8％。睾丸精原细胞瘤患者的1年、3年、5年生存率分别为100％、96.6％、86.5％；睾丸非精原细胞瘤患者的1年、3年、5年生存率分别为98.7％、92.3％、80.2％，不同病理类型患者的1年、3年、5年生存率存在统计学差异（P＜0.0001）；不同病理类型的患者术后辅以不同的治疗方式1年、3年、5年生存率亦存在统计学差异（P＜0.05）。结论：睾丸生殖细胞肿瘤患者的1年、3年、5年生存率与病理类型及术后辅助治疗方式有关，睾丸精原细胞瘤患者的1年、3年、5年生存率高于睾丸非精原细胞瘤患者。%Objectives:To analyze the survival rate of testicular germ cell tumor patients receiving testis sparing surgery after 1 year,3 years and 5 years.Method:Using the retrospective analysis method,We collected and analyzed the clinical data of 1 10 patients who had testicular germ cell tumor resection in our hospital from Octo-ber 1998 to October.2008.The 1,3 and 5 years’survival rates were analyzed for different pathological types and different postoperative adjuvant therapy.Results:In this study,1 -year survival rate of 1 10 patients with testicular germ cell tumor after partial hepatectomy was 99.8%;3-year survival rate was 92.8% and 5 -year survival rate was 87.8%.Survival rates of testicular seminoma in 1 year,3 years and 5 years were 100%,96.6%and 86.5%respectively;survival rates of testicular non -seminoma germ cell tumor in 1 year,3 years and 5 years were 98.7%,92.3%,and 80.2% respectively.Patients with different pathological types after 1 year,3 years and 5 years showed significant difference in the survival rate (P<0.0001);patients with different pathological types also had significant difference in the 3 years and 5 years survival rate (P<0.05 ).Conclusion:For patients with testic-ular germ cell tumor,auxiliary treatment and pathological types affect the 1 -year,3 -year and 5 -year survival rates.The survival rate of testicular seminoma patients in 1 year,3 years and 5 years are higher than of testicular non-seminoma patients.